Many years ago Wilamowitz desiderated a systematic collection of the texts which relate to the different types of poetry composed by the great lyric poets of Greece. He hoped that if we could only crystallize our admittedly scanty information about the characteristics of, say, the Paean or the Dirge, we might be able to reach a slightly better understanding than we have now of the formal structure and artistic design of the poems and fragments which have come down to us (...) under these titles. Indeed, this kind of knowledge is very important. (shrink)

Summary The young Hermann Helmholtz, in an 1838 letter home, declared that he always appreciated music much more when he played it for himself. Though a frequent concert-goer, and celebrated for his highly influential 1863 work on the physiological basis of music theory, Die Lehre von den Tonempfindungen, it is likely that Helmholtz's enduring engagement with music began with his initial, personal experience of playing music for himself. I develop this idea, shifting the discussion of Helmholtz's work on sound sensation (...) back to its origins, and examine the role of his material interaction with musical instruments and music itself. In his sound sensation studies, Helmholtz understood sound as an external, physical object. But Helmholtz also conceived of sound in musical terms. Further, Helmholtz's particular musical tastes as well as his deeply personal interaction with musical instruments allowed him to reconcile his conception of sound as physical object with his conception of sound as music. Helmholtz's physiological theory of sound sensation was both the product of and constitutive of how he heard and created sound. I argue that Helmholtz himself was the embodied reconciliation of his physiological theory of sound sensation and his belief that musical aesthetics were historically and culturally contingent. (shrink)

When a man has breathed his last, do particles of the soul remain in the body or do they not? If they do, the soul, thus impaired by loss, cannot fairly be deemed immortal; if they do not, whence come the living creatures which are bred in carcases?

There can, I think, be little dispute that the most exciting plays about Philoctetes are those which have been described by Bowra, Kitto, and now B. M. W. Knox. It is a matter for regret that we must choose between them, or even reject all of them, since only one play is in question, the Philoctetes of Sophocles. My purpose, however, is not to compare the merits of these rivals, but something more restricted and rather duller. I shall make use (...) of them in reexamining the difficulties raised by Sophocles' handling of the prophecy of Helenus, for it is to these that they largely owe their origin. (shrink)

In our commentary we ask whether we should ultimately endeavour to find the deep causes of behaviours? Then we discuss two extensions of the proposed framework: (1) Mendelian randomisation and (2) hypothesis-free gene–environment interaction (leveraging heterogeneity in genetic associations). These complementary methods help move us towards second-generation causal knowledge, ultimately understanding mechanistic pathways and identifying more effective intervention targets.

(No abstract is available for this citation).

The poetical remains of Dorotheus, on which I made some comments in the Classical Quarterly vol. ii pp. 47–61, have received from the cod. Vat. Graec. 1056 an increase of ten verses, published by Mr J. Heeg in catal. cod. astrol. Graec. vol. v part iii p. 125 and also in Hermes vol. xlv pp. 316–8.

463 ante 462 VGP et ante corr. ut uidetur U, item adnotator super Lucanum ed. Endtii p. 276 et Statii scholiastes ad Theb. VI 760, qui 462 et 464 coniunctos legerunt. 462 ante 463 MZ et ex corr. U. 463 quam MZPGV, qua ex corr. U. 462 manum VGP, lemma schol. Bern., Statii schol., manus Z et ex corr. U de M non liquet. tempus quo noscere possent VGP et ut uidetur M, adn. sup. Luc, Z , Statii schol. , (...) tempus = q.t.i.r.n.p. lemma schol. Bern., uultusque agnoscere quaerunt ex corr. U, Z2 G2, uultus etiam V2. (shrink)

The origin of marine invertebrate larvae has been an area of controversy in developmental evolution for over a century. Here, we address the question of whether a pelagic “larval” or benthic “adult” morphology originated first in metazoan lineages by testing the hypothesis that particular gene co-option patterns will be associated with the origin of feeding, indirect developing larval forms. Empirical evidence bearing on this hypothesis is derivable from gene expression studies of the sea urchin larval gut of two closely related (...) but differently developing congenerics, Heliocidaris tuberculata (feeding indirect-developing larva) and H. erythrogramma (nonfeeding direct developer), given two subsidiary hypotheses. (1) If larval gut gene expression in H. tuberculata was co-opted from an ancestral adult expression pattern, then the gut expression pattern will remain in adult H. erythrogramma despite its direct development. (2) Genes expressed in the larval gut of H. tuberculata will not have a coordinated expression pattern in H. erythrogramma larvae due to loss of a functional gut. Five structural genes expressed in the invaginating archenteron of H. tuberculata during gastrulation exhibit substantially different expression patterns in H. erythrogramma with only one remaining endoderm specific. Expression of these genes in the adult of H. erythrogramma and larval gut of H. tuberculata, but not in H. erythrogramma larval endoderm, supports the hypothesis that they first played roles in the formation of adult structures and were subsequently recruited into larval ontogeny during the origin and evolution of feeding planktotrophic deuterostome larvae. (shrink)

Freedom to smoke is part and parcel of overall freedom. The former cannot be abrogated without violating the latter. The present paper applies this insight to the regulations placed on the tobacco industry and smoking in general. We find that government interventions into people’s lives regarding smoking are highly incompatible with libertarian principles. We examine many regulations such as prohibiting youths from smoking, preventing second hand smoke, restrictions on advertising, taxing the industry, and liability issues.

When in May 1930, the Council of Trinity College, Cambridge, had to decide whether to renew Wittgenstein's research grant, it turned to Bertrand Russell for an assessment of the work Wittgenstein had been doing over the past year. His verdict: "The theories contained in this new work... are novel, very original and indubitably important. Whether they are true, I do not know. As a logician who likes simplicity, I should like to think that they are not, but from what I (...) have read of them I am quite sure that he ought to have an opportunity to work them out, since, when completed, they may easily prove to constitute a whole new philosophy." "[Philosophical Remarks] contains the seeds of Wittgenstein's later philosophy of mind and of mathematics. Principally, he here discusses the role of indispensable in language, criticizing Russell's The Analysis of Mind. He modifies the Tractatus's picture theory of meaning by stressing that the connection between the proposition and reality is not found in the picture itself. He analyzes generality in and out of mathematics, and the notions of proof and experiment. He formulates a pain/private-language argument and discusses both behaviorism and the verifiability principle. The work is difficult but important, and it belongs in every philosophy collection."—Robert Hoffman, Philosophy "Any serious student of Wittgenstein's work will want to study his Philosophical Remarks as a transitional book between his two great masterpieces. The Remarks is thus indispensible for anyone who seeks a complete understanding of Wittgenstein's philosophy."—Leonard Linsky, American Philosophical Association. (shrink)

The 2002 Dutch Euthanasia law applies to patients aged 12 years and older. Developments in end-of-life care and decision-making in the last decade have sparked the debate about usefulness and necessity to extend euthanasia to include children under 12 years of age. This paper describes two opposite positions: the affirmative position of a pediatrician and expert in pediatric palliative care and the negative position of a jurist and specialist in health law.

Quantum frameworks for modeling competitive ecological systems and self-organizing structures have been investigated under multiple perspectives yielded by quantum mechanics. These comprise the description of the phase-space prey–predator competition dynamics in the framework of the Weyl–Wigner quantum mechanics. In this case, from the classical dynamics described by the Lotka–Volterra (LV) Hamiltonian, quantum states convoluted by statistical gaussian ensembles can be analytically evaluated. Quantum modifications on the patterns of equilibrium and stability of the prey–predator dynamics can then be identified. These include (...) quantum distortions over the equilibrium point drivers of the LV dynamics which are quantified through the Wigner current fluxes obtained from an onset Hamiltonian background. In addition, for gaussian ensembles highly localized around the equilibrium point, stability properties are shown to be affected by emergent topological quantum domains which, in some cases, could lead either to extinction and revival scenarios or to the perpetual coexistence of both prey and predator agents identified as quantum observables in microscopic systems. Conclusively, quantum and gaussian statistical driving parameters are shown to affect the stability criteria and the time evolution pattern for such microbiological-like communities. (shrink)

In this paper the analysis of the classical dynamics of a charged particle is carried out without considering that the electromagnetic field necessarily goes to zero at infinity. A quite general non-linear equation of motion is obtained for an extended charged particle valid for any distribution of charge in the particle and for an electromagnetic field satisfying any boundary conditions. Some common approximations are analyzed with detail to determine how the usual difficulties arise.